Digestive Comfort

Digestive Comfort

Several studies support the natural softness and digestive benefits of whole goat milk formula

A prospective cohort study of 976 Korean infants from birth to 12 months found that whole goat milk formula led to more similar stool consistency and frequency than breastfed infants, compared to cow milk formula.1


Whole goat milk formula, cow milk formula and breastmilk comparison of stool frequency and consistency1

Adapted from Han Y, et al. 20111

Mean reduction in regurgitation frequency (times/week) from randomisation to 4 weeks

A trend towards a greater reduction in parent–reported infant regurgitation was observed in infants transitioning from breastfeeding to whole goat milk formula, compared to standard cow milk formula. A total of 80 infants were randomised to investigate the impact on regurgitation frequency over 4 weeks when transitioning from breastfeeding to formula feeding. Despite a higher regurgitation frequency in the whole goat milk formula group at baseline, both groups had similar regurgitation frequency after 4 weeks.2

Adapted from Suteerojntrakool O et al. 2025 2
*P =0.09. Results show a trend towards a significance only.

Unique attributes of Capricare® for digestive comfort

Naturally soft curd due to lower alpha-S1 casein levels

Human milk naturally forms a soft curd in the stomach thanks to its naturally lower levels* of a protein called alpha-S1 casein (~5% of protein5). Like human milk, the goat milk used in Capricare® also has naturally lower levels* of alpha-S1 casein (~8%4), also leading to a naturally soft curd.5 Cow milk forms a harder curd5, due to higher levels alpha-S1 casein (~28%6) – adding whey to cow formulas helps soften the curd5 and makes it easier to digest for infants. Whole goat milk formula is naturally soft without needing to add whey.

Goat milk used in Capricare® is naturally lower in alpha-S1 casein 3-6, making it easier to digest

alpha-S1 casein as % of total protein

Naturally A2 for digestive comfort

Just like human milk, goat milk naturally only contains A2-type beta caseins and no A1-type beta caseins.7



A1-type beta caseins are only present in bovine milk and have been linked to digestive discomfort8,9 and gut inflammation.9 This is because A1-type beta caseins in cow milk release high levels of a peptide called beta-casomorphin 7 (BCM-7), which has been linked to the negative effects of A1-type beta caseins.9


Milk only containing A2-type beta casein has been shown to release no or very little BCM-79 and provides benefits for digestive comfort, stool consistency and frequency.8,9
A2 beta-casein contains Proline at position 67, while A1 beta-casein has Histidine, making A1 more susceptible to enzymatic cleavage and the release of BCM-7 during digestion.

Higher levels of sn-2 palmitic acid* for softer stools

Capricare® contains ~50% fat from the goat milk source naturally providing higher levels of palmitic acid in the sn-2 position**10, which has been linked to digestive benefits, including softer stools, and less crying.11



When palmitic acid is in the sn-1 or sn-3 position of a triglyceride (the main form of fat), it is cleaved by digestive enzyme and becomes a free fatty acid that then forms soaps with calcium, making both the calcium and fatty acid unavailable to be absorbed by the body. This leads to harder stools and lowers calcium absorption. Palmitic acid in the sn-2 position does not form soaps and gets easily absorbed.11
Proportion of palmitic acid in the sn-2 position


References

1 Han et al. Nutr Res Pract 2011;5(4): 308-312
2 Suteerojntrakool et al. (2025, February 20-22). [Oral presentation abstract]. Nutrition & Growth Conference, Athens, Greece
3 Liao et al. J Proteome Res 2017;16: 4113-4121
4 Data on File. Unpublished.
5 Wang et al. Food Hydrocolloids 2019;96: 161-170
6 Amalfitano et al. J Dairy Sci  2020;103: 11190-11208
7 Rahmatalla et al. Front Genet 2022;13: 995349
8 Sheng et al. J Pediatr Gastroenterol Nutr 2019;69(3): 375-3
9 Brooke-Taylor et al. Adv Nutr 2017;8(5): 739-748
10 Gallier et al. Nutrients 2020;12: 3486
11 Miles & Calder. Nutr Res 2017;44: 1-8

*When compared to standard formulas with vegetable oil as source of fat
**When compared to cow milk formula